Is tirzepatide the same as Ozempic?

No. Tirzepatide is a dual agonist targeting both GIP and GLP-1 receptors, while Ozempic targets only GLP-1. Clinical trials consistently show greater weight reduction with tirzepatide compared to semaglutide.

What are the disadvantages of tirzepatide?

Main disadvantages include high cost without insurance, weekly injections, gastrointestinal side effects during dose escalation, and weight regain upon discontinuation without sustained lifestyle changes.

Who cannot take tirzepatide?

Tirzepatide is contraindicated in patients with medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Not approved during pregnancy or breastfeeding.

Does tirzepatide burn fat or just suppress appetite?

Both. Tirzepatide suppresses appetite, slows gastric emptying, improves insulin sensitivity, and has direct effects on fat metabolism through GIP receptor activation.

How many kg can you lose on tirzepatide?

The SURMOUNT-1 trial showed participants on 15mg lost an average of 22.5% body weight over 72 weeks. For a 100kg person that is approximately 22.5kg.

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